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promoter mutations contribute to tumorigenesis in the two-stage mechanism. Individuals mutations in the Preliminary stage, as an alternative to avoiding bulk telomere shortening, extend the cellular lifespan by stabilizing the shortest telomeres. Why is telomerase "switched off" in the

y?llarda ya?lanma ve ya?l?l??a ba?l? hastal?klar ile ilgili ara?t?rmalara yap?lan yat?r?m ciddi bir artwork?? göstermektedir. Pek çok insan ya?lanmak istemiyor, hatta ya?lanmay? önlemek için medikal ve cerrahi esteti?in yan? s?ra ba?ka yöntemlere ba?vuruyor. Son gün

the telomerase subunit Est1p has not too long ago been shown to become able to converting solitary-stranded telomeric G-abundant DNA right into a G-quadruplex structure in vitro Not too long ago, our group has shown that the N-terminus of TIN2 harbors mitochondrial localization alerts, that may t

Telomerik birle?meler, mitoz s?ras?nda k?r?lan disentrik kromozomlar?n olu?mas?na sebep olarak kromozom köprülerinin, k?r?klar?n?n ve birle?melerin olu?mas?n? sa?larlar. Sonuçta hayatta kalan hücrelerin genomlar?nda de?i?iklikler olur. The lagging strand is copied as a resul